• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文OA文献 >Papillomavirus antibody prevalence in free-ranging and captive bottlenose dolphins (Tursiops truncatus)
【2h】

Papillomavirus antibody prevalence in free-ranging and captive bottlenose dolphins (Tursiops truncatus)

机译：乳头状瘤病毒抗体自由放养和圈养宽吻海豚（ Tursiops truncatus ）

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Genital epithelial tumors of Atlantic bottlenose dolphins ( [Tt]) and Burmeister's porpoises () were formerly shown to be associated with papillomavirus (PV) infection. Papillomaviruses are highly prevalent viruses involved in the development of various tumor types in a wide range of animals, and so-called high-risk PVs contribute to malignant progression. In marine mammals, the incidence and prevalence of PV infection, transmission pathways, and persistence of infection are largely unknown. Using virus-like particles of bottlenose dolphin PV type 1 (TtPV1) as the antigen, enzyme-linked immunosorbent assay (ELISA) studies were conducted to evaluate PV antibody prevalence in bottlenose dolphins. In total, sera obtained from 115 dolphins were examined. Fifty-one percent of captive dolphins (=18 of 35) and 90% of free-ranging dolphins (=72 of 80) were antibody positive. Higher ELISA reactivity was observed among males compared with females. Sexually immature dolphins appeared more likely to seroconvert with age. Besides determining their PV antibody prevalence, each animal was also assessed for the presence of orogenital tumors. Interestingly, the mean age of free-ranging dolphins with tumors (=21) was 11.2 yr compared with 29.9 yr in captive dolphins with tumors (=9). Results from the current study suggest PV infection in bottlenose dolphins is common, that the main route of PV transmission among them may be horizontal, and that orogenital neoplasia may develop in early life stages of certain free-ranging bottlenose dolphins.
机译：以前，大西洋宽吻海豚（[Tt]）和Burmeister的海豚（）的生殖器上皮肿瘤与乳头瘤病毒（PV）感染有关。乳头瘤病毒是高度流行的病毒，参与了多种动物的各种肿瘤类型的发展，所谓的高风险PV促成恶性进展。在海洋哺乳动物中，PV感染的发生和流行，传播途径以及感染的持续性在很大程度上是未知的。使用宽吻海豚PV 1型病毒样颗粒（TtPV1）作为抗原，进行了酶联免疫吸附测定（ELISA）研究，以评估宽吻海豚中PV抗体的流行程度。总共检查了从115只海豚获得的血清。 51％的圈养海豚（= 35中的18）和90％的自由放养海豚（= 80中的72）是抗体阳性。与女性相比，男性的ELISA反应性更高。性未成熟的海豚似乎随着年龄的增长而发生血清转化。除了确定其PV抗体的患病率外，还对每只动物的生殖器肿瘤进行了评估。有趣的是，有肿瘤的自由放养海豚的平均年龄（= 21）为11.2岁，而有肿瘤的圈养海豚的平均年龄为29.9岁（= 9）。当前研究的结果表明，宽吻海豚的PV感染很常见，它们之间的PV传播的主要途径可能是水平的，在某些自由放宽的宽吻海豚的生命早期，可能会发生生殖器肿瘤。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号